Guarente Lab Blog http://libert.scripts.mit.edu/bloggy The Science of Aging Tue, 23 Mar 2010 20:12:26 +0000 en-US hourly 1 http://wordpress.org/?v=3.4.1 Alzheimer’s http://libert.scripts.mit.edu/bloggy/?p=4 http://libert.scripts.mit.edu/bloggy/?p=4#comments Fri, 18 Jul 2008 18:13:03 +0000 admin http://libert.scripts.mit.edu/bloggy/?p=4 As MSNBC reports (I did not read the original article in Lancet yet), experimental vaccine against Alzheimer’s was successfully developed and tried on a number of Alzheimer’s patients, most of which were followed till their death up to 6 years. Vaccine was designed to clear the brain from a-beta plaques. It did just that as post-mortem analysis showed. The problem is … those patients did not get any less dementia nor lived any longer. The most obvious conclusion – plaques do not cause Alzheimer’s or dementia, they are either protective or irrelevant for patho-physiology of the disease.

I am thinking that counting plaques as the measure of Alzheimer’s severity in mice is very misleading at this point, and might get exponentially more complicated to publish.

]]> http://libert.scripts.mit.edu/bloggy/?feed=rss2&p=4 0 Welcome to the Guarente Web Blog! http://libert.scripts.mit.edu/bloggy/?p=1 http://libert.scripts.mit.edu/bloggy/?p=1#comments Fri, 18 Jul 2008 14:22:34 +0000 admin http://scripts.mit.edu/~libert/bloggy/?p=1 Hi guys. God Admin is talking. Welcome to the Guarente lab blog!  

Here we are going to discuss lab issues and science of aging.

Anyone can comment on anything already posted right away, by clicking “comment” below. If you want to write and post a new article you have to register by clicking “register” on the right. You can post text and pictures.

Happy Blogging!

]]> http://libert.scripts.mit.edu/bloggy/?feed=rss2&p=1 0